The Challenge

The Parasite

The New World Screwworm (Cochliomyia hominivorax) affects hundreds of millions of wild and domestic animals across South America each year.

After female flies lay eggs in wounds or natural openings, the larvae feed on living tissue, causing severe distress and pain. Without treatment, mortality rates range from 20-80%.

Adult Screwworm Fly
Adult New World Screwworm Fly
Screwworm Larvae
Screwworm Larvae

Beyond the substantial animal welfare concerns, screwworm causes over $3.5 billion in annual losses for South American livestock producers through:

  • Reduced productivity
  • Prevention costs
  • Animal deaths

This parasitic fly represents both a major source of animal suffering and a significant threat to agriculture in the region.

The Infection

Infected Deer

WARNING: Graphic content - Infected wound on live deer

Severe screwworm infestation in deer (graphic medical content)

Infected Dead Deer

WARNING: Graphic content - Fatal wound on deer

Fatal screwworm infestation in deer (graphic medical content)

Human Infection

WARNING: Graphic content - Human infection

Human screwworm infection (graphic medical content)

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Scope of Impact

89.2B

Wild mammals potentially affected across South America

$150M

Annual economic impact in Uruguay alone

76%

Of agricultural operations affected by seasonal impacts

Technical Approach

Gene Drive Technology

  • CRISPR/Cas9 based population control
  • Proven effectiveness in similar applications
  • Minimal environmental impact
  • Cost-effective implementation

Implementation Strategy

  • Cross-border coordination
  • Regional genetic variation consideration
  • Comprehensive monitoring systems
  • Sustainable long-term solution

About Us

We are a philanthropically-funded organization working in partnership with academics, industry, and policymakers across North and South America to tackle the New World Screwworm.

Have questions or want to get involved? Reach out to us using the form below.